A leading researcher provides a comprehensive review of the basic physiology of the hemostatic system, offering a solid foundation for understanding the pathological events leading up to thrombosis and abnormal bleeding. An introductory chapter, intended for the nonspecialist, outlines the whole hemostatic process and leads the reader carefully into the detailed information that follows. The first section of the book describes basic components of platelet structure and function, the coagulation system, and fibrinolytic enzyme system. The second is a unique discussion of the changes in these components induced by physiological parameters—hormones, sex, environment, nutrition, stress, and activity.

Derek Ogston performs an invaluable service in reviewing pertinent studies that show both positive and negative results and examining conflicting data and conclusions. His work will be a source of insight and data for practicing hematologists as well as researchers in this rapidly growing field.