A comprehensive history of abortion in Renaissance Italy.

In this authoritative history, John Christopoulos provides a provocative and far-reaching account of abortion in sixteenth- and seventeenth-century Italy. His poignant portraits of women who terminated or were forced to terminate pregnancies offer a corrective to longstanding views: he finds that Italians maintained a fundamental ambivalence about abortion. Italians from all levels of society sought, had, and participated in abortions. Early modern Italy was not an absolute anti-abortion culture, an exemplary Catholic society centered on the “traditional family.” Rather, Christopoulos shows, Italians held many views on abortion, and their responses to its practice varied.

Bringing together medical, religious, and legal perspectives alongside a social and cultural history of sexuality, reproduction, and the family, Christopoulos offers a nuanced and convincing account of the meanings Italians ascribed to abortion and shows how prevailing ideas about the practice were spread, modified, and challenged. Christopoulos begins by introducing readers to prevailing ideas about abortion and women’s bodies, describing the widely available purgative medicines and surgeries that various healers and women themselves employed to terminate pregnancies. He then explores how these ideas and practices ran up against and shaped theology, medicine, and law. Catholic understanding of abortion was changing amid religious, legal, and scientific debates concerning the nature of human life, women’s bodies, and sexual politics. Christopoulos examines how ecclesiastical, secular, and medical authorities sought to regulate abortion, and how tribunals investigated and punished its procurers—or did not, even when they could have. Abortion in Early Modern Italy offers a compelling and sensitive study of abortion in a time of dramatic religious, scientific, and social change.

The ACA at 10 marks the tenth anniversary of the Affordable Care Act with essays from prominent analysts of US health policy and politics. Its contributors, an interdisciplinary roster of scholars, policymakers, and health policy researchers, explore critical issues and themes in the ACA's evolution. Topics include the role of race in US health politics, the ACA's surprising economic impacts, the history of ACA litigation and its implications for future health reform, the paradoxes of post-ACA Medicaid, shifting directions in public opinion, and much more. Offering a comprehensive accounting of the signal event in US health policy of the last half-century, this issue constitute a landmark contribution to the health politics literature.

Contributors. Daniel Béland, Linda Blumberg, Andrea Louise Campbell, Sherry Glied, Sarah Gordon, Scott Greer, Colleen Grogan, Michael Gusmano, Allison Hoffman, Jon Holahan, Nicole Huberfeld, Lawrence Jacobs, Holly Jarman, David Jones, Timothy Stolzfus Jost, Katie Keith, Aryana Khalid, Larry Levitt, John McDonough, Stacey McMorrow, Suzanne Mettler, Jamila Michener, Jonathan Oberlander, Mark Peterson, Philip Rocco, Marilyn Tavenner, Frank Thompson, Carolyn Hughes Tuohy, Alex Waddan

The ACA at 10 marks the tenth anniversary of the Affordable Care Act with essays from prominent analysts of US health policy and politics. Its contributors, an interdisciplinary roster of scholars, policymakers, and health policy researchers, explore critical issues and themes in the ACA&'s evolution. Topics include the role of race in US health politics, the ACA's surprising economic impacts, the history of ACA litigation and its implications for future health reform, the paradoxes of post-ACA Medicaid, shifting directions in public opinion, and much more. Offering a comprehensive accounting of the signal event in US health policy of the last half-century, this issue constitute a landmark contribution to the health politics literature.

Contributors. John Benson, Robert Blendon, Lawrence Brown, Marc Cohen, Mary Findling, Erika Franklin Fowler, Austin Frakt, Anuj Gangopadhyaya, Bowen Garrett, Sarah Gollust, Simon Haeder, Paula Lantz, Adrianna McIntyre, Edward Miller, James Morone, Pamela Nadash, Jeff Niederdeppe, Sayeh Nikpay, Jonathan Oberlander, Eric Patashnik, India Pungarcher, Sara Rosenbaum, Eric Schneider, Michael Sparer, Joseph White, Susan Webb Yackee

Many people in developing countries lack access to health technologies, even basic ones. Why do these problems in access persist? What can be done to improve access to good health technologies, especially for poor people in poor countries?

This book answers those questions by developing a comprehensive analytical framework for access and examining six case studies to explain why some health technologies achieved more access than others. The technologies include praziquantel (for the treatment of schistosomiasis), hepatitis B vaccine, malaria rapid diagnostic tests, vaccine vial monitors for temperature exposure, the Norplant implant contraceptive, and female condoms.

Based on research studies commissioned by the Bill & Melinda Gates Foundation to better understand the development, adoption, and uptake of health technologies in poor countries, the book concludes with specific lessons on strategies to improve access. These lessons will be of keen interest to students of health and development, public health professionals, and health technology developers—all who seek to improve access to health technologies in poor countries.

Concerns about access to behavioral health care for military service members and their dependents living in geographically remote locations prompted research into how many in this population are remote and the effects of this distance on their use of behavioral health care. The authors conducted geospatial and longitudinal analyses to answer these questions and reviewed current policies and programs to determine barriers and possible solutions.

Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening tests for inherited disorders, gene therapies, and the ability to manipulate a person's inherited, non-disease traits. Most of the attention given to the social implications of these technologies has focused on their potential to harm the individual, for example, by denying employment or insurance.

This book explores instead the potential harm to society if we unfairly distribute the enormous benefits of genetic technologies. The resulting division of society into genetic haves and have-nots would undermine the basic foundation of Western democratic society—the belief in equality of opportunity.

This book explains, in terms that can be understood by the general reader, how DNA works, what the Human Genome Project is, what these genetic technologies are and what they promise, and how they could disrupt our democratic society.

In an original contribution to the literature, the book then discusses the alternatives for avoiding the creation of a genetic underclass, ranging from halting the Human Genome Project itself to making genetic technologies available without regard to ability to pay. The authors' provocative conclusion is that a lottery in which everyone has a chance to obtain access to these technologies is the only feasible option.

This book will be of interest to anyone who wishes to learn more about the Human Genome Project and the genetic revolution that it will create, as well as those who already are familiar with the project and are concerned about the social consequences of its scientific developments.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones.

To which this book says: Pure nonsense. In a work at once deeply learned and wonderfully accessible, the neuroscientist David Linden counters the widespread assumption that the brain is a paragon of design--and in its place gives us a compelling explanation of how the brain's serendipitous evolution has resulted in nothing short of our humanity. A guide to the strange and often illogical world of neural function, The Accidental Mind shows how the brain is not an optimized, general-purpose problem-solving machine, but rather a weird agglomeration of ad-hoc solutions that have been piled on through millions of years of evolutionary history. Moreover, Linden tells us how the constraints of evolved brain design have ultimately led to almost every transcendent human foible: our long childhoods, our extensive memory capacity, our search for love and long-term relationships, our need to create compelling narrative, and, ultimately, the universal cultural impulse to create both religious and scientific explanations. With forays into evolutionary biology, this analysis of mental function answers some of our most common questions about how we've come to be who we are.

According to a recent Institute of Medicine report, as many as 98,000 Americans die each year as a result of medical error—a figure higher than deaths from automobile accidents, breast cancer, or AIDS. That astounding number of fatalities does not include the number of those serious mistakes that are grievous and damaging but not fatal. Who can forget the tragic case of 17-year-old Jésica Santillán, who died after receiving a heart-lung transplant with an incompatible blood type? What can be done about this? What should be done? How can patients and their families regain a sense of trust in the hospitals and clinicians that care for them? Where do we even begin the discussion?

Accountability brings the issue to the table in response to the demand for patient safety and increased accountability regarding medical errors. In an interdisciplinary approach, Virginia Sharpe draws together the insights of patients and families who have suffered harm, institutional leaders galvanized to reform by tragic events in their own hospitals, philosophers, historians, and legal theorists. Many errors can be traced to flaws in complex systems of health care delivery, not flaws in individual performance. How then should we structure responsibility for medical mistakes so that justice for the injured can be achieved alongside the collection of information that can improve systems and prevent future error? Bringing together authoritative voices of family members, health care providers, and scholars—from such disciplines as medical history, economics, health policy, law, philosophy, and theology—this book examines how conventional structures of accountability in law and medical structure (structures paradoxically at odds with justice and safety) should be replaced by more ethically informed federal, state, and institutional policies. Accountability calls for public policy that creates not only systems capable of openness concerning safety and error—but policy that also delivers just compensation and honest and humane treatment to those patients and families who have suffered from harmful medical error.

Popular understanding holds that genetic changes create cancer. James DeGregori uses evolutionary principles to propose a new way of thinking about cancer’s occurrence. Cancer is as much a disease of evolution as it is of mutation, one in which mutated cells outcompete healthy cells in the ecosystem of the body’s tissues. His theory ties cancer’s progression, or lack thereof, to evolved strategies to maximize reproductive success.

Through natural selection, humans evolved genetic programs to maintain bodily health for as long as necessary to increase the odds of passing on our genes—but not much longer. These mechanisms engender a tissue environment that favors normal stem cells over precancerous ones. Healthy tissues thwart cancer cells’ ability to outcompete their precancerous rivals. But as our tissues age or accumulate damage from exposures such as smoking, normal stem cells find themselves less optimized to their ecosystem. Cancer-causing mutations can now help cells adapt to these altered tissue environments, and thus outcompete normal cells. Just as changes in a species’ habitat favor the evolution of new species, changes in tissue environments favor the growth of cancerous cells.

DeGregori’s perspective goes far in explaining who gets cancer, when it appears, and why. While we cannot avoid mutations, it may be possible to sustain our tissues’ natural and effective system of defense, even in the face of aging or harmful exposures. For those interested in learning how cancers arise within the human body, the insights in Adaptive Oncogenesis offer a compelling perspective.

In a book sure to inspire controversy, Gene Heyman argues that conventional wisdom about addiction—that it is a disease, a compulsion beyond conscious control—is wrong.

Drawing on psychiatric epidemiology, addicts’ autobiographies, treatment studies, and advances in behavioral economics, Heyman makes a powerful case that addiction is voluntary. He shows that drug use, like all choices, is influenced by preferences and goals. But just as there are successful dieters, there are successful ex-addicts. In fact, addiction is the psychiatric disorder with the highest rate of recovery. But what ends an addiction?

At the heart of Heyman’s analysis is a startling view of choice and motivation that applies to all choices, not just the choice to use drugs. The conditions that promote quitting a drug addiction include new information, cultural values, and, of course, the costs and benefits of further drug use. Most of us avoid becoming drug dependent, not because we are especially rational, but because we loathe the idea of being an addict.

Heyman’s analysis of well-established but frequently ignored research leads to unexpected insights into how we make choices—from obesity to McMansionization—all rooted in our deep-seated tendency to consume too much of whatever we like best. As wealth increases and technology advances, the dilemma posed by addictive drugs spreads to new products. However, this remarkable and radical book points to a solution. If drug addicts typically beat addiction, then non-addicts can learn to control their natural tendency to take too much.

Addiction is now seen as an ordinary feature of human nature, an idea that introduces new doubts about the meaning of our desires.
 
Over the last forty years, a variety of developments in American science, politics, and culture have reimagined addiction in their own ways, but they share an important understanding: increasingly, addiction is described as normal, the natural result of a body that has been exposed to potent stimuli. This shift in thinking suggests that addiction is a condition latent in all of us, a common response to a society rich in thrills.
 
In Addiction Becomes Normal, Jaeyoon Park provides a history and critical analysis of the normalization of addiction in late-modern American society. By exploring addiction science, diagnostic manuals, judicial reform, and public health policy, he shows how seeing addiction as normal has flourished in recent decades and is supported throughout cultural life in the United States by the language of wellness, psychotherapy, and more. Building on Michel Foucault’s depiction of the human figure, Park argues that this shift reflects the emergence of a new American subject, one formed by the accretion of experiences. This view of the human subject challenges the idea that our compulsions reflect our characters, wills, or spirits. For if addiction is an extreme but ordinary attachment, and if compulsive consumption resembles healthy behavior, then desire is no longer an expression of the soul so much as the pursuit of a past reward. A perceptive work of recent history and political theory, Addiction Becomes Normal raises new questions about what it means to be human in America today.

This is an auto-narrated audiobook version of this book.

Addiction is now seen as an ordinary feature of human nature, an idea that introduces new doubts about the meaning of our desires.
 
Over the last forty years, a variety of developments in American science, politics, and culture have reimagined addiction in their own ways, but they share an important understanding: increasingly, addiction is described as normal, the natural result of a body that has been exposed to potent stimuli. This shift in thinking suggests that addiction is a condition latent in all of us, a common response to a society rich in thrills.
 
In Addiction Becomes Normal, Jaeyoon Park provides a history and critical analysis of the normalization of addiction in late-modern American society. By exploring addiction science, diagnostic manuals, judicial reform, and public health policy, he shows how seeing addiction as normal has flourished in recent decades and is supported throughout cultural life in the United States by the language of wellness, psychotherapy, and more. Building on Michel Foucault’s depiction of the human figure, Park argues that this shift reflects the emergence of a new American subject, one formed by the accretion of experiences. This view of the human subject challenges the idea that our compulsions reflect our characters, wills, or spirits. For if addiction is an extreme but ordinary attachment, and if compulsive consumption resembles healthy behavior, then desire is no longer an expression of the soul so much as the pursuit of a past reward. A perceptive work of recent history and political theory, Addiction Becomes Normal raises new questions about what it means to be human in America today.

Inducing highs of excitement, anger, and terror, adrenaline fuels the extremes of human experience. A rush empowers superhuman feats in emergencies. Risk-taking junkies seek to replicate this feeling in dangerous recreations. And a surge may literally scare us to death. Adrenaline brings us up to speed on the fascinating molecule that drives some of our most potent experiences.

Adrenaline was discovered in 1894 and quickly made its way out of the lab into clinics around the world. In this engrossing account, Brian Hoffman examines adrenaline in all its capacities, from a vital regulator of physiological functions to the subject of Nobel Prize–winning breakthroughs. Because its biochemical pathways are prototypical, adrenaline has had widespread application in hormone research leading to the development of powerful new drugs. Hoffman introduces the scientists to whom we owe our understanding, tracing the paths of their discoveries and aspirations and allowing us to appreciate the crucial role adrenaline has played in pushing modern medicine forward.

Hoffman also investigates the vivid, at times lurid, place adrenaline occupies in the popular imagination, where accounts of its life-giving and lethal properties often leave the realm of fact. Famous as the catalyst of the “fight or flight” response, adrenaline has also received forensic attention as a perfect poison, untraceable in the bloodstream—and rumors persist of its power to revive the dead. True to the spirit of its topic, Adrenaline is a stimulating journey that reveals the truth behind adrenaline’s scientific importance and enduring popular appeal.

Do people of differing ethnicities, cultures, and races view medicine and bioethics differently? And, if they do, should they? Are doctors and researchers taking environmental perspectives into account when dealing with patients? If so, is it done effectively and properly?

In African American Bioethics, Lawrence J. Prograis Jr. and Edmund D. Pellegrino bring together medical practitioners, researchers, and theorists to assess one fundamental question: Is there a distinctive African American bioethics?

The book's contributors resoundingly answer yes—yet their responses vary. They discuss the continuing African American experience with bioethics in the context of religion and tradition, work, health, and U.S. society at large—finding enough commonality to craft a deep and compelling case for locating a black bioethical framework within the broader practice, yet recognizing profound nuances within that framework.

As a more recent addition to the study of bioethics, cultural considerations have been playing catch-up for nearly two decades. African American Bioethics does much to advance the field by exploring how medicine and ethics accommodate differing cultural and racial norms, suggesting profound implications for growing minority groups in the United States.

By analyzing the amalgam of Greek philosophy, Jewish and Christian teachings, and secular humanism that composes our dominant ethical system, the authors of this volume explore the question of whether or not Western and non-Western moral values can be commingled without bilateral loss of cultural integrity. They take as their philosophical point of departure the observation that both ethical relativism and ethical absolutism have become morally indefensible in the context of the multicultural American life, and they variously consider the need for an ethical middle ground.

What will become of our earthly remains? What happens to our bodies during and after the various forms of cadaver disposal available? Who controls the fate of human remains? What legal and moral constraints apply? Legal scholar Norman Cantor provides a graphic, informative, and entertaining exploration of these questions. After We Die chronicles not only a corpse’s physical state but also its legal and moral status, including what rights, if any, the corpse possesses.

In a claim sure to be controversial, Cantor argues that a corpse maintains a “quasi-human status" granting it certain protected rights—both legal and moral. One of a corpse’s purported rights is to have its predecessor’s disposal choices upheld. After We Die reviews unconventional ways in which a person can extend a personal legacy via their corpse’s role in medical education, scientific research, or tissue transplantation. This underlines the importance of leaving instructions directing post-mortem disposal. Another cadaveric right is to be treated with respect and dignity. After We Die outlines the limits that “post-mortem human dignity” poses upon disposal options, particularly the use of a cadaver or its parts in educational or artistic displays.

Contemporary illustrations of these complex issues abound. In 2007, the well-publicized death of Anna Nicole Smith highlighted the passions and disputes surrounding the handling of human remains. Similarly, following the 2003 death of baseball great Ted Williams, the family in-fighting and legal proceedings surrounding the corpse’s proposed cryogenic disposal also raised contentious questions about the physical, legal, and ethical issues that emerge after we die. In the tradition of Sherwin Nuland's How We Die, Cantor carefully and sensitively addresses the post-mortem handling of human remains.

“If you want to understand how the latest advances in genomics and AI can completely transform your health, and to translate this promise into practical tools that you can apply today, read this book!”—Mark Hyman, author of Young Forever

Taking us to the cutting edge of the new frontier of medicine, a visionary biotechnologist and a pathbreaking researcher show how we can optimize our health in ways that were previously unimaginable.

We are on the cusp of a major transformation in healthcare—yet few people know it. At top hospitals and a few innovative health-tech startups, scientists are working closely with patients to dramatically extend their “healthspan”—the number of healthy years before disease sets in. In The Age of Scientific Wellness, two visionary leaders of this revolution in health take us on a thrilling journey to this new frontier of medicine.

Today, most doctors wait for clinical symptoms to appear before they act, and the ten most commonly prescribed medications confer little or no benefit to most people taking them. Leroy Hood and Nathan Price argue that we must move beyond this reactive, hit-or-miss approach to usher in real precision health—a form of highly personalized care they call “scientific wellness.” Using information gleaned from our blood and genes and tapping into the data revolution made possible by AI, doctors can catch the onset of disease years before symptoms arise, revolutionizing prevention. Current applications have shown startling results: diabetes reversed, cancers eliminated, Alzheimer’s avoided, autoimmune conditions kept at bay.

This is not a future fantasy: it is already happening, but only for a few patients and at high cost. It’s time to make this gold standard of care more widely available. Inspiring in its possibilities, radical in its conclusions, The Age of Scientific Wellness shares actionable insights to help you chart a course to a longer, healthier, and more fulfilling life.

Seniors today find themselves living in a time when rapid changes in health care delivery have made vital decisions about when and how best to obtain medical treatment difficult and confusing to navigate. At the same time, seniors proportionately need more health care services, have a higher incidence of chronic disease, and take more medications than any other demographic—and yet have the lowest rate of health literacy.

AIDS and the Distribution of Crises engages with the AIDS pandemic as a network of varied historical, overlapping, and ongoing crises born of global capitalism and colonial, racialized, gendered, and sexual violence. Drawing on their investments in activism, media, anticolonialism, feminism, and queer and trans of color critiques, the scholars, activists, and artists in this volume outline how the neoliberal logic of “crisis” structures how AIDS is aesthetically, institutionally, and politically reproduced and experienced. Among other topics, the authors examine the writing of the history of AIDS; settler colonial narratives and laws impacting risk in Indigenous communities; the early internet regulation of both content and online AIDS activism; the Black gendered and sexual politics of pleasure, desire, and (in)visibility; and how persistent attention to white men has shaped AIDS as intrinsic to multiple, unremarkable crises among people of color and in the Global South.

Contributors. Cecilia Aldarondo, Pablo Alvarez, Marlon M. Bailey, Emily Bass, Darius Bost, Ian Bradley-Perrin, Jih-Fei Cheng, Bishnupriya Ghosh, Roger Hallas, Pato Hebert, Jim Hubbard, Andrew J. Jolivette, Julia S. Jordan-Zachery, Alexandra Juhasz, Dredge Byung'chu Kang-Nguyễn, Theodore (Ted) Kerr, Catherine Yuk-ping Lo, Cait McKinney, Viviane Namaste, Elton Naswood, Cindy Patton, Margaret Rhee, Juana María Rodríguez, Sarah Schulman, Nishant Shahani, C. Riley Snorton, Eric A. Stanley, Jessica Whitbread, Quito Ziegler

Lucid and compellingly written, Patricia Siplon has immersed herself in the history and ongoing firestorms of how AIDS policies are influenced, fought over, and enacted in the United States. AIDS and the Policy Struggle in the United States is equally as engrossing and as revealing in its own way as And the Band Played On. With an initial chapter that clearly follows the tangled historical string from the first realizations of a medical emergency to today's overwhelming worldwide epidemical crisis, she goes on to look at how medical treatments have changed and grown; how blood policies were formed; how value-based debates raged and continue to rage over prevention; how communities developed to first respond to the crisis, and later organized to fight for health care; and finally-now that AIDS is recognized for the global crisis it is-how foreign policy is being shaped.

Invaluable for activists and anyone involved in fighting for the humane treatment of people with HIV/AIDS around the world, this is also an important and insightful guide to the how and what of public policy as it is fashioned out of the clay of U.S. democratic institutions.

AIDS is unquestionably the most serious threat to public health in this century--yet how effective has the United States been in coping with this deadly disease? This sobering analysis of the first five years of the AIDS epidemic reveals the failure of traditional approaches in recognizing and managing this health emergency; it is an extremely unsettling probe into what makes the nation ill equipped to handle a crisis of the magnitude of the one that now confronts us.

Sandra Panem pays particular attention to the Public Health Service, within which the vast majority of biomedical research and public health services are organized, including the Centers for Disease Control and the National Institutes of Health. We learn in dismaying detail how shortcomings in communication within and among the many layers of the health establishment delayed management of the crisis.

She also investigates other problems that surface during a health emergency, involving issues such as federal budgeting, partisan politics, bureaucratic bungles, educating the public, the complications of policymaking, and the vexing role of the press. Panem makes specific recommendations for a centrally coordinated federal response to health emergencies, including the creation of a national health emergency plan.

Every minute a Nigerian man, woman, or child becomes infected with HIV. Soon Nigeria will be home to more people living with HIV than any other country in Africa. With 5 percent of its inhabitants already infected, Nigeria has reached the critical threshold that can catapult rates to nearly 40 percent of a country's population. The full magnitude of Nigeria's epidemic will be determined by its response now.

AIDS in Nigeria helps guide that response. Written by dozens of the country's leading HIV experts, the book explores the dynamics of the epidemic, analyzes prevention efforts, identifies crucial gaps, and formulates effective strategies for controlling the epidemic. Complementing the experts' words are the dramatic portraits of people whose lives have been forever transformed by AIDS. Their stories reveal the human costs of the epidemic--and the courage required to overcome it.

The impact of the AIDS pandemic on health systems and entire societies in the 1990s will be much more severe than it was in the last decade; up-to-date information about the disease is now crucial. Yet even though readers are deluged by technical publications and popularizations, no single book tracks, on an annual basis, the evolution of the pandemic, its effects, and the worldwide response.

To fill this gap, Jonathan Mann, founding director of the World Health Organization's Global Progam on AIDS and currently director of the International AIDS Center at Harvard University, has assembled a team of experts to produce an unprecedented document for our time. AIDS in the World will synthesize the best possible information, data, and thinking about AIDS into a volume that is destined to become a landmark publication. AIDS in the World will provide a vital guide to rekindling the worldwide assault on AIDS. To ensure that AIDS in the World 1992 is both timely and authoritative, the editors have enlisted the support of an extensive team of researchers, specialists, scientists, writers, and experts to provide a solid basis for new and original thinking on a wide range of topics.

This book reviews the status of the disease, including numbers of AIDS cases and deaths; AIDS and HIV prevalence; mortality rates; links between other infections and HlV breakthroughs in biomedical, clinical, and behavioral areas; prevention and care; legislation and human rights issues; and economic and demographic aspects. AIDS in the World 1992 provides a global assessment for where we are now and where we are headed; it spotlights critical issues and highlights communities and countries that may be especially vulnerable to the dissemination of HIV. With publication scheduled before the VIIIth International Conference on AIDS in July 1992, this work will be indispensable for governments, policymakers, scientists, health care workers, and journalists around the world who will rely on this book to make the crucial decisions of this decade and the next.

We have made huge progress in understanding the biology of mental illnesses, but comparatively little in interpreting them at the psychological level. The eminent philosopher Jonathan Glover believes that there is real hope of progress in the human interpretation of disordered minds.

The challenge is that the inner worlds of people with psychiatric disorders can seem strange, like alien landscapes, and this strangeness can deter attempts at understanding. Do people with disorders share enough psychology with other people to make interpretation possible? To explore this question, Glover tackles the hard cases—the inner worlds of hospitalized violent criminals, of people with delusions, and of those diagnosed with autism or schizophrenia. Their first-person accounts offer glimpses of inner worlds behind apparently bizarre psychiatric conditions and allow us to begin to learn the “language” used to express psychiatric disturbance. Art by psychiatric patients, or by such complex figures as van Gogh and William Blake, give insight when interpreted from Glover’s unique perspective. He also draws on dark chapters in psychiatry’s past to show the importance of not medicalizing behavior that merely transgresses social norms. And finally, Glover suggests values, especially those linked with agency and identity, to guide how the boundaries of psychiatry should be drawn.

Seamlessly blending philosophy, science, literature, and art, Alien Landscapes? is both a sustained defense of humanistic psychological interpretation and a compelling example of the rich and generous approach to mental life for which it argues.

This book--intended to dispel the mystique and folklore surrounding arthritis--is the first to explain clearly the scientific aspects of arthritis research and treatment. Brewerton tells the intriguing story of arthritis research, from the days before germs were recognized as causes of disease and when reasons for inflammation were obscure, to the present, when breakthroughs in genetics, epidemiology, X-ray crystallography, cell biology, and molecular biology support major advances in research and treatment. He also addresses the human element, discussing the role in arthritis of such factors as age, gender, emotions, pain, and personality. Brewerton ends the story on a hopeful note, carefully explaining the prospects for prevention and treatment.

Roman Catholic moral theology is the point of departure for this multifaceted exploration of the challenge of allocating scarce medical resources.

The volume begins its exploration of discerning moral limits to modern high-technology medicine with a consensus statement born of the conversations among its contributors. The seventeen essays use the example of critical care, because it offers one of the few areas in medicine where there are good clinical predictive measures regarding the likelihood of survival. As a result, the health care industry can with increasing accuracy predict the probability of saving lives—and at what cost.

Because critical care involves hard choices in the face of finitude, it invites profound questions about the meaning of life, the nature of a good death, and distributive justice. For those who identify the prize of human life as immortality, the question arises as to how much effort should be invested in marginally postponing death. In a secular culture that presumes that individuals live only once, and briefly, there is an often-unacknowledged moral imperative to employ any means necessary to postpone death. The conflict between the free choice of individuals and various aspirations to equality compounds the challenge of controlling medical costs while also offering high-tech care to those who want its possible benefits. It forces society to confront anew notions of ordinary versus extraordinary, and proportionate versus disproportionate, treatment in a highly technologically structured social context.

This cluster of discussions is enriched by five essays from Jewish, Orthodox Christian, and Protestant perspectives. Written by premier scholars from the United States and abroad, these essays will be valuable reading for students and scholars of bioethics and Christian moral theology.

A leading bioethicist offers critical insights into the scientific, ethical, and political implications of human genome editing.

Designer babies, once found only in science fiction, have become a reality. We are entering a new era of human evolution with the advent of a technology called CRISPR, which allows scientists to modify our genes. Although CRISPR shows great promise for therapeutic use, it raises thorny ethical, legal, political, and societal concerns because it can be used to make permanent changes to future generations. What if changes intended for the good turn out to have unforeseen negative effects? What if the divide between the haves and have-nots widens as a result? Who decides whether we genetically modify human beings and, if so, how?

Françoise Baylis insists that we must all have a role in determining our future as a species. The scientists who develop and use genome-editing tools should not be the only ones making decisions about future uses of the technology. Such decisions must be the fruit of a broad societal consensus. Baylis argues that it is in our collective interest to assess and steer the development and implementation of biomedical technologies. Members of the public with different interests and diverse perspectives must be among the decision makers; only in this way can we ensure that societal concerns are taken into account and that responsible decisions are made. We must be engaged and informed, think critically, and raise our voices as we create our future together.

Sharp, rousing, timely, and thought-provoking, Altered Inheritance is essential reading. The future of humanity is in our hands.

A bracing spotlight on the avoidable causes of the COVID-19 Eldercide in the United States.
 
Twenty percent of the Americans who have died of COVID since 2020 have been older and disabled adults residing in nursing homes—even though they make up fewer than one percent of the US population. Something about this catastrophic loss of life in government-monitored facilities has never added up.
 
Until now. In American Eldercide, activist and scholar Margaret Morganroth Gullette investigates this tragic public health crisis with a passionate voice and razor-sharp attention to detail, showing us that nothing about it was inevitable. By unpacking the decisions that led to discrimination against nursing home residents, revealing how governments, doctors, and media reinforced ageist or ableist biases, and collecting the previously little-heard voices of the residents who survived, Gullette helps us understand the workings of what she persuasively calls an eldercide.
 
Gullette argues that it was our collective indifference, fueled by the heightened ageism of the COVID-19 era, that prematurely killed this vulnerable population. Compounding that deadly indifference is our own panic about aging and a social bias in favor of youth-based decisions about lifesaving care. The compassion this country failed to muster for the residents of our nursing facilities motivated Gullette to pen an act of remembrance, issuing a call for pro-aging changes in policy and culture that would improve long-term care for everyone.

In 1895 there was not a single case of dementia praecox reported in the United States. By 1912 there were tens of thousands of people with this diagnosis locked up in asylums, hospitals, and jails. By 1927 it was fading away . How could such a terrible disease be discovered, affect so many lives, and then turn out to be something else?

In vivid detail, Richard Noll describes how the discovery of this mysterious disorder gave hope to the overworked asylum doctors that they could at last explain—though they could not cure—the miserable patients surrounding them. The story of dementia praecox, and its eventual replacement by the new concept of schizophrenia, also reveals how asylum physicians fought for their own respectability. If what they were observing was a disease, then this biological reality was amenable to scientific research. In the early twentieth century, dementia praecox was psychiatry’s key into an increasingly science-focused medical profession.

But for the moment, nothing could be done to help the sufferers. When the concept of schizophrenia offered a fresh understanding of this disorder, and hope for a cure, psychiatry abandoned the old disease for the new. In this dramatic story of a vanished diagnosis, Noll shows the co-dependency between a disease and the scientific status of the profession that treats it. The ghost of dementia praecox haunts today’s debates about the latest generation of psychiatric disorders.

In the second half of the nineteenth century, American cities began to go dark. Hulking new buildings overspread blocks, pollution obscured the skies, and glass and smog screened out the health-giving rays of the sun. Doctors fed anxities about these new conditions with claims about a rising tide of the "diseases of darkness," especially rickets and tuberculosis.

In American Sunshine, Daniel Freund  tracks the obsession with sunlight from those bleak days into the twentieth century.  Before long, social reformers, medical professionals, scientists, and a growing nudist movement proffered remedies for America’s new dark age. Architects, city planners, and politicians made access to sunlight central to public housing and public health. and entrepreneurs, dairymen, and tourism boosters transformed the pursuit of sunlight and its effects into a commodity. Within this historical context, Freund sheds light on important questions about the commodification of health and nature and makes an original contribution to the histories of cities, consumerism, the environment, and medicine.

Hippocrates, said to have been born in Cos in or before 460 BCE, learned medicine and philosophy; travelled widely as a medical doctor and teacher; was consulted by King Perdiccas of Macedon and Artaxerxes of Persia; and died perhaps at Larissa. Apparently he rejected superstition in favour of inductive reasoning and the study of real medicine as subject to natural laws, in general and in individual people as patients for treatment by medicines and surgery. Of the roughly 70 works in the “Hippocratic Collection,” many are not by Hippocrates; even the famous oath may not be his. But he was undeniably the “Father of Medicine.”

The works available in the Loeb Classical Library edition of Hippocrates are:

Volume I: Ancient Medicine. Airs, Waters, Places. Epidemics 1 and 3. The Oath. Precepts. Nutriment.
Volume II: Prognostic. Regimen in Acute Diseases. The Sacred Disease. The Art. Breaths. Law. Decorum. Physician (Ch. 1). Dentition.
Volume III: On Wounds in the Head. In the Surgery. On Fractures. On Joints. Mochlicon.
Volume IV: Nature of Man. Regimen in Health. Humours. Aphorisms. Regimen 1–3. Dreams.
Volume V: Affections. Diseases 1–2.
Volume VI: Diseases 3. Internal Affections. Regimen in Acute Diseases.
Volume VII: Epidemics 2 and 4–7.
Volume VIII: Places in Man. Glands. Fleshes. Prorrhetic 1–2. Physician. Use of Liquids. Ulcers. Haemorrhoids and Fistulas.
Volume IX: Anatomy. Nature of Bones. Heart. Eight Months’ Child. Coan Prenotions. Crises. Critical Days. Superfetation. Girls. Excision of the Fetus. Sight.
Volume X: Generation. Nature of the Child. Diseases 4. Nature of Women. Barrenness.
Volume XI: Diseases of Women 1–2.

(Volume IV also contains the fragments of Heracleitus’ On the Universe.)

A groundbreaking reassessment of existing research and new data on traditional botanical medicine.

Traditional medical systems continue to impact the lives of people around the globe. These systems vary greatly in their underlying beliefs, but all commonly rely on the consumption of plant matter as a central practice. An Ancient Mesopotamian Herbal is a new, fully illustrated book that explores the uses of plants in traditional medicine and how these botanical roots extend to modern, “conventional” medicinal treatments.

Divided into two parts, An Ancient Mesopotamian Herbal introduces the lands and ancient cultures of Mesopotamia before surveying the different forms of evidence and research methods informing this academic book. The book then looks to the modern day, focusing on thirty case studies of plant-based drugs. Bridging the divide between the humanities and sciences and using new research and data from modern-day Iraq and surrounding areas, An Ancient Mesopotamian Herbal draws on the expertise of archeo-botanists, scientists, and Assyriologists specializing in historic Mesopotamian medicine to provide new identifications of Assyrian and Babylonian herbal medicines while giving a concise overview of ancient Mesopotamian herbal lore.
 

A revisionist biography of Andreas Vesalius—the father of modern anatomy—as deeply shaped by Renaissance culture.
 
In 1543 the young and ambitious physician Andreas Vesalius published one of the most famous books in the history of medicine, On the Fabric of the Human Body. While we often think of dissection as destroying the body, Vesalius believed that it helped him understand how to construct the human body. In this book, Sachiko Kusukawa shows how Vesalius’s publication emerged from the interplay of Renaissance art, printing technology, and classical tradition. She challenges the conventional view of Vesalius as a proto-modern, anti-authoritarian father of anatomy through a more nuanced account of how Vesalius exploited cultural and technological developments to create a big and beautiful book that propelled him into imperial circles and secured his enduring fame.

Since the turn of the new millennium, ‘translational research’, the scientific process of bringing disease-targeted knowledge from the laboratory to treat patients in the clinic, has gone mainstream and is now practiced by large universities and institutes across the globe.  Into this dynamic of the rapidly changing world of translational medical research this book sets the life of one of the discipline’s most influential practitioners, Anthony Cerami. His work spans more than five decades and culminated in the discovery, invention and development of diagnostics and therapeutics used daily by millions of people. Students in molecular medicine and investigators pursuing basic science in the hope of improving human health will find inspiration in examining the sacrifices and achievements of Cerami’s career in translational medicine. During his three decades at Rockefeller University his cross-disciplinary and laboratory-without-wall approach established ‘rational drug design’ as the most effective means of advancing the fields of parasitology, hematology, immunology, metabolism, therapeutics and molecular medicine. Cerami’s story and that of the evolution of translation are intimately entwined: the contours of Cerami’s career shaped by developments in translation, and in exchange, the field itself molded by Cerami’s work.  To understand one is to understand the other. By examining the life of this often overlooked biochemist it is possible to intimately focus on the ideas and thought processes of a scientist who has helped to define the great acceleration in translational research over the past half century – research that, knowingly or otherwise, has most likely affected the life of almost everyone on the planet.  We also gain a better understanding of the febrile creative atmosphere that percolated through the laboratories leading the way in translational medicine, and gain insight into the art, science, successes, failures and providence that underlie major scientific breakthroughs.  Anybody interested in the questions of where modern medicines come from, how health outcomes around the globe are affected by research and imagination, and where the future of drug discovery is leading, will be rewarded by exploring Cerami’s life in translation.  This book is not restricted to those with a professional interest in science, because anyone dedicated to living a life of creativity and discovery will be rewarded by reading this book.  In many respects, Cerami’s life reflects the modern metaphor of the ‘American dream’ with his journey from humble beginnings on a chicken farm in rural New Jersey, to occupying a place in  the highest echelons of the US scientific establishment.  His journey in translational medicine was propelled forward by two obsessions; the idea that he could help people who were sick, and the excitement of discovery. In following his two great passions, he trained a generation of specialists in translational medicine that continue to transform our understanding of, and treatments for, human disease.  Anthony Cerami’s work has shown how science has become an important force for social change by laying the foundations of modern translational medicine.
 

Why do we eat? Is it instinct? Despite the necessity of food, anxieties about what and how to eat are widespread and persistent. In Appetite and Its Discontents, Elizabeth A. Williams explores contemporary worries about eating through the lens of science and medicine to show us how appetite—once a matter of personal inclination—became an object of science.
 
Williams charts the history of inquiry into appetite between 1750 and 1950, as scientific and medical concepts of appetite shifted alongside developments in physiology, natural history, psychology, and ethology. She shows how, in the eighteenth century, trust in appetite was undermined when researchers who investigated ingestion and digestion began claiming that science alone could say which ways of eating were healthy and which were not. She goes on to trace nineteenth- and twentieth-century conflicts over the nature of appetite between mechanists and vitalists, experimentalists and bedside physicians, and localists and holists, illuminating struggles that have never been resolved. By exploring the core disciplines in investigations in appetite and eating, Williams reframes the way we think about food, nutrition, and the nature of health itself..

The radically humanistic essays in Arc of Interference refigure our sense of the real, the ethical, and the political in the face of mounting social and planetary upheavals. Creatively assembled around Arthur Kleinman’s medical anthropological arc and eschewing hegemonic modes of intervention, the essays advance the notion of a care-ful ethnographic praxis of interference. To interfere is to dislodge ideals of naturalness, blast enduring binaries (human/nonhuman, self/other, us/them), and redirect technocratic agendas while summoning relational knowledge and the will to create community. The book’s multiple ethnographic arcs of interference provide a vital conceptual toolkit for today’s world and a badly needed moral perch from which to peer toward just horizons.

Contributors. Vincanne Adams, João Biehl, Davíd Carrasco, Lawrence Cohen, Jean Comaroff, Robert Desjarlais, Paul Farmer, Marcia Inhorn, Janis H. Jenkins, David S. Jones, Salmaan Keshavjee, Arthur Kleinman, Margaret Lock, Adriana Petryna

A new history of the medieval illustrations that birthed modern anatomy.
 
This book is the first history of medieval European anatomical images. Richly illustrated, The Art of Anatomy in Medieval Europe explores the many ways in which medieval surgeons, doctors, monks, and artists understood and depicted human anatomy. Taylor McCall refutes the common misconception that Renaissance artists and anatomists such as Leonardo da Vinci and Andreas Vesalius were the fathers of anatomy who performed the first human dissections. On the contrary, she argues that these Renaissance figures drew upon centuries of visual and written tradition in their works.
 

During the past few decades, high-profile cases like that of Terry Schiavo have fueled the public debate over forgoing or withdrawing artificial nutrition and hydration from patients in a persistent vegetative state (PVS). These cases, whether involving adults or young children, have forced many to begin thinking in a measured and careful way about the moral legitimacy of allowing patients to die. Can families forgo or withdraw artificial hydration and nutrition from their loved ones when no hope of recovery seems possible?

Many Catholics know that Catholic moral theology has formulated a well-developed and well-reasoned position on this and other end-of-life issues, one that distinguishes between "ordinary" and "extraordinary" treatment. But recent events have caused uncertainty and confusion and even acrimony among the faithful. In his 2004 allocution, Pope John Paul II proposed that artificial nutrition and hydration is a form of basic care, thus suggesting that the provision of such care to patients neurologically incapable of feeding themselves should be considered a moral obligation. The pope's address, which seemed to have offered a new development to decades of Catholic health care ethics, sparked a contentious debate among the faithful over how best to treat permanently unconscious patients within the tenets of Catholic morality.

In this comprehensive and balanced volume, Ronald Hamel and James Walter present twenty-one essays and articles, contributed by physicians, clergy, theologians, and ethicists, to reflect the spectrum of perspectives on the issues that define the Catholic debate. Organized into six parts, each with its own introduction, the essays offer clinical information on PVS and feeding tubes; discussions on the Catholic moral tradition and how it might be changing; ecclesiastical and pastoral statements on forgoing or withdrawing nutrition and hydration; theological and ethical analyses on the issue; commentary on Pope John Paul II's 2004 allocution; and the theological commentary, court decisions, and public policy resulting from the Clarence Herbert and Claire Conroy legal cases.

A valuable resource for students and scholars, this teachable volume invites theological dialogue and ethical discussion on one of the most contested issues in the church today.

People are living longer, creating an unexpected boom in the elderly population. Longevity is increasing not only in wealthy countries but in developing nations as well. In response, many policy makers and scholars are preparing for a global crisis of aging. But for too long, Western experts have conceived of aging as a universal predicament—one that supposedly provokes the same welfare concerns in every context. In the twenty-first century, Kavita Sivaramakrishnan writes, we must embrace a new approach to the problem, one that prioritizes local agendas and values.

As the World Ages is a history of how gerontologists, doctors, social scientists, and activists came to define the issue of global aging. Sivaramakrishnan shows that transnational organizations like the United Nations, private NGOs, and philanthropic foundations embraced programs that reflected prevailing Western ideas about development and modernization. The dominant paradigm often assumed that, because large-scale growth of an aging population happened first in the West, developing societies will experience the issues of aging in the same ways and on the same terms as their Western counterparts. But regional experts are beginning to question this one-size-fits-all model and have chosen instead to recast Western expertise in response to provincial conditions. Focusing on South Asia and Africa, Sivaramakrishnan shows how regional voices have argued for an approach that responds to local needs and concerns. The research presented in As the World Ages will help scholars, policy makers, and advocates appreciate the challenges of this recent shift in global demographics and find solutions sensitive to real life in diverse communities.